Naukowcy z Uniwersytetu Stanowego w Pensylwanii opracowali innowacyjny czujnik wielkości ćwierćdolarówki, który służy pomiarowi glukozy krwi na postawie potu jego użytkownika. Wynalazek jest nieinwazyjny, mocowany na skórze za pomocą bezpiecznego kleju.
Długotrwała hiperglikemia może być przyczyną poważnych powikłań w zakresie leczenia ran, dlatego monitoring poziomu cukru we krwi jest istotny dla profilaktyki i leczenia ran w cukrzycy. Obecnie większość diabetyków mierzy poziom glukozy za pomocą glukometru, który polega na nakłuciu palca, lub za pomocą wszczepianych podskórnie czujników. Eksperymentalne narzędzie opracowane na Uniwersytecie Stanowym Pensylwanii może wkrótce zrewolucjonizować ten proces, mierząc poziom glukozy za pomocą czujnika przymocowanego do powierzchni skóry użytkownika.
Monitorowanie glukozy bez igieł
Naukowcy opracowali już prototyp urządzenia i przeprowadzili pierwsze badania jego skuteczności. Urządzenie zostało umieszczone na ramieniu ochotnika za pomocą bezpiecznego dla skóry kleju. Odczyty wykonano godzinę oraz trzy godziny po spożyciu posiłku. Tuż przed odczytami uczestnik badań wykonał krótki trening, by wytworzyć niewielką ilość potu. Czujnik wskazał poziomy glukozy zgodne z tymi uzyskanymi za pomocą glukometru.
– Chcemy współpracować z lekarzami i innymi pracownikami ochrony zdrowia, aby zobaczyć, jak możemy zastosować tę technologię do codziennego monitorowania poziomu glukozy we krwi pacjenta – mówi Prof. Huanyu „Larry” Cheng, główny autor badania.
Eksperci podkreślają, że urządzenie jest niedrogie i nieinwazyjne. Naukowcy planują również ulepszyć czujnik i dostosować go do potrzeb pacjentów i klinicystów.
Niezwykle czułe urządzenie
Monitorowanie poziomu glukozy we krwi na podstawie potu zostało również opisane w innych badaniach. Podobne czujniki opracowali m.in. naukowcy z University of Texas, University of Cincinnati, Institute for Basic Science w Korei, Fraunhofer Institute for Microelectronic Circuits and Systems w Niemczech.
Badacze z Uniwersytetu Stanowego Pensylwanii podkreślają jednak, iż ważne jest, by zwiększać precyzję wykrywania glukozy we krwi na podstawie potu. Czujnik został więc zaprojektowany tak, żeby być niezwykle czułym na glukozę i dokładnie wykrywać jej poziom.
Urządzenie zawiera w sobie elektrodę piankową wykonaną z grafenu, pokrytą stopem złota i niklu – pierwiastka metalicznego silnie wrażliwego na glukozę. Poprzez niewielki otwór urządzenie pobiera pot użytkownika i przenosi go do komory mikroprzepływowej wypełnionej roztworem alkaicznym. System zaprojektowano w taki sposób, by roztwór ten nie miał bezpośredniego kontaktu ze skórą. Cząsteczki glukozy, które obecne są w pocie reagują z roztworem alkaicznym tworząc związek, który następnie kierowany jest do elektrody piankowej. Tam, w reakcji z niklem, powstaje sygnał elektryczny. Mierząc siłę tego sygnału urządzenie jest w stanie ustalić poziom glukozy w pocie, a tym samym w krwiobiegu.
Źródło: news.psu.edu
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