Leczenie ran oparzeniowych to w wielu przypadkach długotrwały i utrudniony proces. Badania wskazują, że proces gojenia oparzeń można wesprzeć poprzez stosowanie kolagenu w formie iniekcji in-situ w brzegi rany.
Kolagen to białko, które odgrywa istotną rolę w procesie gojenia ran. Jako podstawowy budulec skóry właściwej bierze udział m.in. w procesach proliferacji i remodelingu tkanek. Kolagen wykazuje skuteczność w stymulowaniu procesów naskórkowania, obkurczania się rany i ziarninowania. Pozytywne efekty stosowania kolagenu w formie iniekcji in-situ w brzegi rany zostały potwierdzone zarówno w badaniach, jak i w praktyce klinicznej.
Poniżej przedstawiamy case study z terapii z zastosowaniem iniekcji z tropokolagenu na rany oparzeniowe w obrębie głowy. Autorami studium przypadku są lek. Mateusz Kęsek (MK Aesthetic Med Clinic Gliwice) oraz dr n. med. Agata Biedulska (Oddział Chirurgii Plastycznej, WSS nr 5 im. św. Barbary w Sosnowcu, Centrum Urazowe; Oddział Małoinwazyjnej Chirurgii i Traumatologii Wieku Rozwojowego, Centrum Pediatrii im. Jana Pawła II w Sosnowcu).
Opis przypadku
Dziewczynka w wieku 4 lat, bez obciążeń. W procesie diagnostycznym wykluczono swoiste zapalenia naczyń oraz pęcherzyce.
U pacjentki wystąpiła przewlekła rana oparzeniowa obejmująca prawą okolicę skroniową, czołową i ciemieniową, z centralnym, jątrzącym owrzodzeniem w przebiegu tętnicy skroniowej powierzchownej. Keloid okolicy przedusznej prawej.
W leczeniu ambulatoryjnym stosowano opatrunki specjalistyczne oraz środki o działaniu przeciwdrobnoustrojowym, w tym również miejscowe antybiotyki. Dziecko objęto również leczeniem w ośrodku HBO. W czasie leczenia obserwowano infekcję rany P. aeruginosa, którą leczono z powodzeniem antybiotykoterapią. Stosowano również naświetlania lampą LED oraz laseroterapię laserem frakcyjnym CO2. Wobec braku efektów zastosowanych terapii zdecydowano o próbie leczenia Tropokolagenem GUNA. Pomiędzy zabiegami stosowano na ranę środek antyseptyczny oraz natłuszczanie emolientem.
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