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Lavanid® – płyn do irygacji i oczyszczania ran ostrych i przewlekłych firmy Serag-Wiessner

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Lavanid® to sterylny, izoosmotyczny roztwór do miejscowego nawadniania ran ostrych i przewlekłych o zróżnicowanej etiologii. Produkt nadaje się również do stosowania śródoperacyjnego, a także do nawilżania wymazów, okładów i opatrunków.

Jak działa produkt Lavanid®?

Płyn do irygacji ran Lavanid® to sterylny, izoosmotyczny roztwór na bazie płynu Ringera z dodatkiem poliheksanidu (PHMB). Płyn występuje w dwóch rodzajach: roztwór Lavanid 1 zawiera poliheksanid w stężeniu 0,02%, natomiast płyn Lavanid 2 zawiera 0,04% poliheksanidu.

Dzięki izotonicznym właściwościom płynu podczas stosowania nie zachodzi wymiana płynu ani elektrolitów z wydzielinami organizmu, co zapobiega powstawaniu obrzęków wokół rany oraz podrażnieniom. Połączenie płynu Ringera i 0,04% poliheksanidu, które zostało wykorzystane w roztworze, zapewnia produktowi bardzo dobrą tolerancję tkankową. Produkt nie ma działania cytotoksycznego. Znacznie redukuje lub całkowicie znosi dolegliwości bólowe pacjenta. Wpływa pozytywnie na regenerację tkanek i tworzącą się ziarninę, przyspieszając tym samym gojenie rany. Poliheksanid działa dużo korzystniej w ranie przewlekłej niż PVP-jod i dichlowodorek octenidyny.[1]

Zawarty w składzie produktu poliheksanid wpływa na zmniejszenie napięcia powierzchniowego roztworu, dzięki czemu możliwe jest skuteczne dotarcie do tkanek w obszarze rany i oczyszczenie ich.

Ponadto poliheksanid hamuje namnażanie się drobnoustrojów w opatrunkach oraz w roztworze, dzięki czemu zapobiega zakażeniom. Działanie poliheksanidu polega na selektywnym oddziaływaniu na cytoplazmę i błonę cytoplazmatyczną oraz uszkadzaniu DNA drobnoustrojów. Poliheksanid wykazuje skuteczność przeciwko szerokiemu spektrum mikroorganizmów. Zwalcza bakterie Gram-ujemne i Gram-dodatnie, w tym również szczepy oporne takie jak MRSA i VRE, bakterie przetrwalnikujące i wewnątrzkomórkowe, grzyby oraz wirusy. Poliheksanid jest także skuteczny w niszczeniu biofilmu. Według najnowszych wytycznych PHMB to środek antyseptyczny pierwszego wyboru w leczeniu ran krytycznie skolonizowanych i zakażonych oraz oparzeń.[2]

PHMB jest również skuteczną alternatywą dla antybiotyków działających miejscowo oraz prowadzi do redukcji bólu. [1,3]

Stosowanie płynu pozwala ponadto na zmniejszenie ilości włóknika i wysięku w łożysku rany, poprawę mikrokrążenia oraz skuteczne nawilżenie rany, dzięki czemu wspiera procesy gojenia. Dzięki właściwościom odkażającym i przeciwdrobnoustrojowym Lavanid® skutecznie eliminuje brzydki zapach z rany.

Lavanid® nie powoduje reakcji alergicznych i anafilaktycznych oraz rozwijania się odporności bakteryjnej. Płyn nadaje się do użytku przez 2 miesiące od pierwszego otwarcia opakowania, natomiast żel przez 1 miesiąc od otwarcia.

Na jakie rany można stosować płyn Lavanid®?

Płyn Lavanid® może być stosowany do oczyszczania i irygacji ran trudno gojących się takich jak owrzodzenia na podłożu cukrzycowym, odleżyny, owrzodzenia podudzi na tle niewydolności żylnej. Można go również stosować na rany o wysokim poziomie wrażliwości, takie jak oparzenia I i II stopnia.

Lavanid® może być również stosowany do przemywania ran ostrych, w tym również ran chirurgicznych. Produkt nadaje się także do stosowania śródoperacyjnego, a także w zapobieganiu zakażeniu miejsca operowanego.

Produkt jest również odpowiedni do leczenia ran zakażonych lub zagrożonych zakażeniem, w tym do zakażeń w obrębie endoprotezy oraz ostrych zakażeń kostnych i tkanek miękkich.

Do leczenia początkowego, ran ostrych i silnie zainfekowanych zaleca się płyn Lavanid 2 (0,04 proc. poliheksanidu). W ranach z rozwiniętym procesem gojenia, do płukania jam ciała, w miejscach zagrożonych infekcją oraz w terapii podciśnieniowej stosuje się natomiast płyn Lavanid 1 (0,02% poliheksanidu).

Przeciwwskazania w stosowaniu

Płyn Lavanid® nie powinien być stosowany w obrębie centralnego układu nerwowego oraz opon mózgowych. Nie zaleca się również stosowania produktu na rany i tkankę chrzęstną, a także w obrębie oczu oraz ucha środkowego i wewnętrznego.

Płyn nie powinien być stosowany we wlewach dootrzewnowych. Nie zaleca się również stosowania produktu u pacjentów ze stwierdzoną nadwrażliwością na poliheksanid.

Opinia eksperta o produkcie Lavanid® – Andrzej Przewięźlikowski, magister pielęgniarstwa chirurgicznego, specjalista w leczeniu ran przewlekłych, prowadzący własną działalność leczenia ran przewlekłych

Lavanid jest preparatem o szerokim zastosowaniu. Jest sterylnym, izoosmotycznym roztworem. W leczeniu ran przewlekłych należy pamiętać, że nie tylko rodzaj substancji czynnej ma znaczenie, ale również jej stężenie. Lavanid jest tego doskonałym przykładem. Dostępne stężenia PHMB w Lavanidzie to: Lavanid 1 – 0,02% i Lavanid 2 – 0,04%. Według badań poliheksanid w tych stężeniach jest antyseptykiem niepodrażniającym. Dzięki temu możliwe jest długotrwałe stosowanie tego preparatu na ranie.

W jaki sposób używać płynu Lavanid®?

Płyn Lavanid® może być dozowany na dwa sposoby: poprzez odkręcenie butelki lub wkłucie w nakrętkę specjalnego kolca. Aby skorzystać z drugiej metody, należy zdjąć folię aluminiową i zdezynfekować miejsce wkłucia kolca. Następnie należy włożyć kolec. W ten sposób butelka z płynem zostaje przygotowana do dozowania aseptycznego.

W celu mechanicznego oczyszczenia rany należy przepłukać ją preparatem Lavanid®. Produkt nadaję się do wielokrotnego i długotrwałego leczenia ran trudno gojących się.

Płyn można również wykorzystywać do nawilżania wymazów, okładów i opatrunków, tamponad i serwet operacyjnych. Stosuje się go także do dekontaminacji pacjentów zakażonych MRSA.

Płyn Lavanid® może być stosowany w terapii podciśnieniowej.

Produkt Lavanid® występuje również w formie żelu na rany, który może być stosowany wspólnie z płynem dla poprawy efektów leczenia.

Jak długo można używać produktu?

Ze względu na swój skład produkty Lavanid nie mają ograniczenia czasowego w  ich zastosowaniu. Ich wskazaniem jest długoterminowa terapia ran.

 

Skuteczność produktu Lavanid® – case study

Chory, lat 27, aktywny zawodowo (kucharz), leczony z powodu owrzodzenia od 6 lat, obciążony otyłością olbrzymią i przewlekłą niewydolnością żylną w stopniu C6 wg klasyfikacji CEAP.

W chwili objęcia opieką owrzodzenie okrężne podudzia lewego od linii kostek do 1/3 górnej jego wysokości, pokryte złogami włóknika wymieszanymi z martwicą rozpływną obficie sączyło, wydzielało przykry zapach. Z relacji chorego wynika, że 6 lat temu pojawiła się niewielka rana w okolicy kostki przyśrodkowej.

W tej fazie leczył się u dermatologa. Pomimo leczenia rana powiększała się i kiedy pojawiła się druga w okolicy kostki bocznej, pacjent został skierowany do chirurga. Stosował wg zaleceń opatrunki specjalistyczne. Mimo to owrzodzenie nadal się powiększało. Ranę chory pielęgnował sam.

Pacjent trudny do współpracy, ze względu na otyłość olbrzymią ograniczone możliwości samopielęgnacji, bardzo żywo reagujący przy próbach oczyszczania rany (wielokrotnie przerywano debridement z powodu silnych dolegliwości bólowych).

Stan rany uległ radykalnej poprawie po wprowadzeniu kompresjoterapii półsztywnej, niestety zrezygnowano z niej mimo dobrych efektów. Ból był nie do zniesienia. Natomiast każda próba wprowadzenia opatrunków aktywnych w połączeniu z kompresjoterapią powodowała nawroty zakażenia generującego duże obszary martwicy.

Zdecydowano o zastosowaniu antyseptyków w przymoczkach zmienianych 2 razy dziennie w połączeniu z kompresjoterapią. Zastosowano podchloryny. Po początkowej poprawie stanu rany po czasie dochodziło do pogorszenia. Wówczas po raz pierwszy zastosowano PHMB w preparacie o stężeniu 0,1%, niestety i tym razem scenariusz się powtórzył.

Radykalną poprawę stanu rany odnotowano dopiero od 06.05.2020 r., kiedy zastosowano Lavanid 2 w stężeniu 0,04% poliheksanidu. Zakażenia i martwica nie nawracają, owrzodzenie powoli, ale sukcesywnie się zmniejsza.

Historia leczenia tego pacjenta zdaje się potwierdzać tezę prof. Kramera, że najlepszym antyseptykiem nie jest ten o najszerszym zastosowaniu, ale ten, który będzie najodpowiedniejszy do danego przypadku. Tak jak nie ma identycznych ran przewlekłych, tak też nie ma idealnego opatrunku, którym można leczyć wszystkie rany. Tym razem Lavanid i kompresjoterapia okazały się najskuteczniejszą metodą leczenia tej konkretnej rany.

Jakie rodzaje produktu są dostępne?

Płyn Lavanid® jest dostępny w butelkach o pojemności 125 ml, 250 ml, 500 ml oraz 1000 ml.

Lavanid Żel na rany jest dostępny w tubach o pojemności: 40 g i 100 g oraz w  strzykawkach o pojemności 10g.

Czy na produkt Lavanid® przysługuje refundacja?

Produkt Lavanid® nie jest refundowany.

Gdzie kupić produkt Lavanid®?

Preparat Lavanid® jest dostępny w aptekach stacjonarnych w większości aptek na terenie kraju oraz na stronie internetowej firmy Surg-Tech –  przedstawiciela producenta produktów Lavanid i Lavanox (podchloryn sodowy) w Polsce.

Można go kupić tu:

https://www.lavanid.com/

Firma Surg-Tech posiada w swojej ofercie nie tylko stale rosnącą gamę produktów do leczenia i pielęgnacji ran, ale również wysokiej jakości sprzęt do chirurgii małoinwazyjnej.

 

Źródła:

[1] Elżbieta Szkiler, Poliheksanid w miejscowym leczeniu ran, „Forum Zakażeń „2018, 9(5), 291-297.

[2] Kramer A., Consensus on Wound Antisepsis: Update 2018.

[3] Gerli S., Rossetti D, Di Renzo G.C. A new approach for the treatment of bacterial vaginosis; use of polyhexamethylene biguanide, „European Review for Medical and Pharmacological Sciences” 2003, 7(5), 127-130.

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    Understanding COSC Accreditation and Its Importance in Horology
    COSC Certification and its Demanding Standards
    Controle Officiel Suisse des Chronometres, or the Controle Officiel Suisse des Chronometres, is the official Switzerland testing agency that certifies the precision and precision of timepieces. COSC validation is a mark of excellent craftsmanship and trustworthiness in chronometry. Not all watch brands seek COSC accreditation, such as Hublot, which instead sticks to its proprietary strict standards with movements like the UNICO, reaching comparable accuracy.

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    Several renowned brands prioritize COSC accreditation for their timepieces, including Rolex, Omega, Breitling, and Longines, among others. Longines, for instance, offers collections like the Archive and Spirit, which showcase COSC-validated movements equipped with cutting-edge substances like silicone balance springs to boost durability and efficiency.

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    The concept of the chronometer dates back to the need for accurate timekeeping for navigational at sea, highlighted by John Harrison’s work in the 18th cent. Since the formal establishment of Controle Officiel Suisse des Chronometres in 1973, the accreditation has become a yardstick for assessing the accuracy of high-end watches, sustaining a tradition of excellence in horology.

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    레버리지 방식의 스탁은 일반적으로 자본을 차입하여 투자하는 방법입니다. 사례를 들어, 100만 원의 투자금으로 1,000만 원 상당의 주식을 취득할 수 있는데, 이는 투자자가 일반적인 투자 금액보다 훨씬 훨씬 더 많은 증권을 사들여, 증권 가격이 상승할 경우 해당하는 더 큰 이익을 획득할 수 있게 합니다. 그렇지만, 주식 값이 하락할 경우에는 그 손실 또한 커질 수 있으므로, 레버리지를 이용할 때는 신중하게 생각해야 합니다.

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    레버리지 사용은 특히 성장 가능성이 큰 기업에 투자할 때 유용합니다. 이러한 사업체에 상당한 비율을 통해 투입하면, 잘 될 경우 큰 이익을 얻을 수 있지만, 반대의 경우 많은 위험도 짊어져야 합니다. 따라서, 투자자는 자신의 리스크 관리 능력과 상장 분석을 통해, 일정한 사업체에 얼마만큼의 투자금을 적용할지 결정하게 됩니다 합니다.

    레버리지의 장점과 위험 요소
    레버리지 스탁은 높은 수익을 제공하지만, 그만큼 높은 위험도 동반합니다. 증권 거래의 변동성은 추정이 힘들기 때문에, 레버리지 사용을 사용할 때는 항상 장터 동향을 정밀하게 관찰하고, 손해를 최소로 줄일 수 있는 전략을 세워야 합니다.

    맺음말: 신중한 선택이 필수입니다
    로드스탁을 통해 제공하는 레버리지 스탁은 막강한 투자 수단이며, 적절히 이용하면 많은 이익을 벌어들일 수 있습니다. 그렇지만 큰 위험도 생각해 봐야 하며, 투자 결정이 충분히 많은 정보와 신중한 고려 후에 이루어져야 합니다. 투자하는 사람의 금융 상황, 위험 수용 능력, 그리고 장터 상황을 반영한 안정된 투자 방법이 중요합니다.

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    Проверка данных кошелька на выявление наличия нелегальных средств: Обеспечение безопасности личного криптовалютного портфельчика

    В мире криптовалют становится все важнее важнее обеспечивать защиту своих финансов. Ежедневно жулики и злоумышленники создают свежие схемы обмана и мошенничества и кражи виртуальных денег. Ключевым инструментом основных методов защиты становится проверка данных бумажников за наличие неправомерных финансовых средств.

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    В первую очередь, вот это важно для того чтобы охраны своих денег. Многие из инвесторы рискуют потерять потери денег своих финансов из-за несправедливых методов или воровства. Проверка кошельков кошельков для хранения криптовалюты способствует предотвращению своевременно выявить непонятные операции и предотвратить возможные.

    Что предлагает вашему вниманию наша фирма?

    Мы предлагаем вам сервис анализа криптовалютных бумажников и транзакций с намерением идентификации источника денег и дать детального отчета о проверке. Компания предлагает платформа проанализировать данные для обнаружения подозрительных операций и оценить риск для того чтобы вашего портфеля. Благодаря нашей проверке, вы можете предотвратить возможные с регуляторными органами и обезопасить от непреднамеренного участия в незаконных операций.

    Как проводится процесс?

    Наша организация взаимодействует с крупными аудиторами фирмами, как например Certik, для того чтобы обеспечить гарантированность и точность наших проверок кошельков. Мы внедряем передовые и методики анализа данных для идентификации опасных манипуляций. Персональные сведения наших заказчиков обрабатываются и сохраняются в соответствии с положениями высокими стандартами безопасности.

    Основной запрос: „проверить свои USDT на чистоту”

    Если вам нужно убедиться в надежности ваших USDT-кошельков, наша компания предоставляет возможность исследовать бесплатную проверку первых пяти кошельков. Просто введите свой кошелек в указанное место на нашем веб-сайте, и мы передадим вам подробные сведения о состоянии вашего кошелька.

    Обеспечьте безопасность своих активы сразу же!

    Предотвращайте риски попасть жертвой мошенников криминальных элементов или стать неприятной ситуации подозрительных операций с вашими собственными финансами. Доверьте свои финансы профессиональным консультантам, которые смогут помочь, вам и вашему бизнесу обезопаситься криптовалютные средства и избежать. Совершите первый шаг к обеспечению безопасности к безопасности личного криптовалютного финансового портфеля прямо сейчас!